Two people were seriously injured in a crash in Lewis County on Friday afternoon. According to a Missouri State Highway Patrol report, a Ford Taurus driven by 38-year-old Gregory Walker, of Hannibal crossed the center line on Route B, one mile south of LaGrange, and struck a Mack semi-trailer driven by 42-year-old Jack Sharkey, of Taylor. Walker was flown to a hospital, while Sharkey was transported by ambulance.